Identify the protein:

• Select search by "NCBI / Swissprot ID"
  
  
• Enter the UniProt Accession PDX1_HUMAN
  
  
• Tick the "Include poteins with the same OrthoMCL ID" checkbox
  
  

• Click on the "Submit Query" button
  

Display graphic view:

• Select all hits found (11 in this case)
  
  

• Click on "Show gene order map(s)" button
  
  
• Click on the "Color clusters by OrthoMCL" button
  
  
  

Identify the RNA:

• Select search by "Phylum"
  
  
• Select "Metazoa"
  
  
• Type "U12 minor spliceosomal RNA" as Rfam description
  
  

• Click on the "Submit Query" button

Retrieve evolutionary conserved pairs of adjacent genes:

• Select the two human genes found (Homsap_00923r010 and Homsap_24128r010)
  
  

• Click on "Show gene order pairs" button
  
  
• Select the row tha thas the bidirectional gene pair:
  • GeneA : Homsap_130457p101
  • GeneB : Homsap_00923r010
  • Orientation : < >
    
    

• Click on the "Conserved gene pairs (OrthoMCL)" button
  
  
• Select all hits found (10 in this case)
  
  

• Click on "Show gene order map(s)" button
  
  

Display graphic view:

• Click on the "Color clusters by OrthoMCL" button
  
  
  

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